Novel Cathelicidins from Pigeon Highlights Evolutionary Convergence in Avain Cathelicidins and Functions in Modulation of Innate Immunity

Cathelicidins are short cationic host defense peptides and play a central role in host innate immune system. Here we identified two novel cathelicidins, Cl-CATH2 and 3, from Columba livia. Evolutionary analysis of avian cathelicidins via phylogenetic tree and Ka/Ks calculations supported the positiv...

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Detalles Bibliográficos
Autores principales: Yu, Haining, Lu, Yiling, Qiao, Xue, Wei, Lin, Fu, Tingting, Cai, Shasha, Wang, Chen, Liu, Xuelian, Zhong, Shijun, Wang, Yipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508531/
https://www.ncbi.nlm.nih.gov/pubmed/26194630
http://dx.doi.org/10.1038/srep11082

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