Cargando…

Long-Term Hearing Outcome After Retrosigmoid Removal of Vestibular Schwannoma

Although many investigators have reported the hearing function in the immediate postoperative period in patients with vestibular schwannoma (VS), little is known about the long-term outcomes of the postoperative hearing. The aim of this study was to analyze the long-term hearing outcomes at a mean f...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakamizo, Akira, Mori, Megumu, Inoue, Daisuke, Amano, Toshiyuki, Mizoguchi, Masahiro, Yoshimoto, Koji, Sasaki, Tomio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Neurosurgical Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508745/
https://www.ncbi.nlm.nih.gov/pubmed/24077269
http://dx.doi.org/10.2176/nmc.oa2012-0351
_version_ 1782381987222257664
author Nakamizo, Akira
Mori, Megumu
Inoue, Daisuke
Amano, Toshiyuki
Mizoguchi, Masahiro
Yoshimoto, Koji
Sasaki, Tomio
author_facet Nakamizo, Akira
Mori, Megumu
Inoue, Daisuke
Amano, Toshiyuki
Mizoguchi, Masahiro
Yoshimoto, Koji
Sasaki, Tomio
author_sort Nakamizo, Akira
collection PubMed
description Although many investigators have reported the hearing function in the immediate postoperative period in patients with vestibular schwannoma (VS), little is known about the long-term outcomes of the postoperative hearing. The aim of this study was to analyze the long-term hearing outcomes at a mean follow-up of 5 years in patients with unilateral VS treated via the retrosigmoid approach. Twenty-four patients with immediate postoperative serviceable hearing who underwent repeated audiogram or phone interview were included in this study. During the mean follow-up period (68.8 ± 30.2 months, range 14–123 months), serviceable hearing was preserved in 20 out of the 24 patients (83%). Pure tone average (PTA) was reevaluated within 6 months in seven patients. In the two patients whose PTA deteriorated ≥ 5 dB in 6 months after surgery, their PTA worsened ≥ 15 dB compared to the immediate postoperative PTA. In the remaining five patients whose PTA deteriorated < 5 dB in 6 months after surgery, PTA was maintained within a 15-dB deterioration at the final follow-up (p = 0.04, Fisher's exact test). According to Kaplan–Meier survival plots, the 5-year or 7-year preservation rate of serviceable hearing was 86.2% or 71.8%, respectively. Further study will be needed to clarify the mechanism underlying the long-term decline of serviceable hearing; however, the deterioration of PTA in the early postoperative period may help to predict the long-term outcomes of hearing.
format Online
Article
Text
id pubmed-4508745
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher The Japan Neurosurgical Society
record_format MEDLINE/PubMed
spelling pubmed-45087452015-11-05 Long-Term Hearing Outcome After Retrosigmoid Removal of Vestibular Schwannoma Nakamizo, Akira Mori, Megumu Inoue, Daisuke Amano, Toshiyuki Mizoguchi, Masahiro Yoshimoto, Koji Sasaki, Tomio Neurol Med Chir (Tokyo) Original Article Although many investigators have reported the hearing function in the immediate postoperative period in patients with vestibular schwannoma (VS), little is known about the long-term outcomes of the postoperative hearing. The aim of this study was to analyze the long-term hearing outcomes at a mean follow-up of 5 years in patients with unilateral VS treated via the retrosigmoid approach. Twenty-four patients with immediate postoperative serviceable hearing who underwent repeated audiogram or phone interview were included in this study. During the mean follow-up period (68.8 ± 30.2 months, range 14–123 months), serviceable hearing was preserved in 20 out of the 24 patients (83%). Pure tone average (PTA) was reevaluated within 6 months in seven patients. In the two patients whose PTA deteriorated ≥ 5 dB in 6 months after surgery, their PTA worsened ≥ 15 dB compared to the immediate postoperative PTA. In the remaining five patients whose PTA deteriorated < 5 dB in 6 months after surgery, PTA was maintained within a 15-dB deterioration at the final follow-up (p = 0.04, Fisher's exact test). According to Kaplan–Meier survival plots, the 5-year or 7-year preservation rate of serviceable hearing was 86.2% or 71.8%, respectively. Further study will be needed to clarify the mechanism underlying the long-term decline of serviceable hearing; however, the deterioration of PTA in the early postoperative period may help to predict the long-term outcomes of hearing. The Japan Neurosurgical Society 2013-10 2013-10-25 /pmc/articles/PMC4508745/ /pubmed/24077269 http://dx.doi.org/10.2176/nmc.oa2012-0351 Text en © 2013 The Japan Neurosurgical Society This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Original Article
Nakamizo, Akira
Mori, Megumu
Inoue, Daisuke
Amano, Toshiyuki
Mizoguchi, Masahiro
Yoshimoto, Koji
Sasaki, Tomio
Long-Term Hearing Outcome After Retrosigmoid Removal of Vestibular Schwannoma
title Long-Term Hearing Outcome After Retrosigmoid Removal of Vestibular Schwannoma
title_full Long-Term Hearing Outcome After Retrosigmoid Removal of Vestibular Schwannoma
title_fullStr Long-Term Hearing Outcome After Retrosigmoid Removal of Vestibular Schwannoma
title_full_unstemmed Long-Term Hearing Outcome After Retrosigmoid Removal of Vestibular Schwannoma
title_short Long-Term Hearing Outcome After Retrosigmoid Removal of Vestibular Schwannoma
title_sort long-term hearing outcome after retrosigmoid removal of vestibular schwannoma
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508745/
https://www.ncbi.nlm.nih.gov/pubmed/24077269
http://dx.doi.org/10.2176/nmc.oa2012-0351
work_keys_str_mv AT nakamizoakira longtermhearingoutcomeafterretrosigmoidremovalofvestibularschwannoma
AT morimegumu longtermhearingoutcomeafterretrosigmoidremovalofvestibularschwannoma
AT inouedaisuke longtermhearingoutcomeafterretrosigmoidremovalofvestibularschwannoma
AT amanotoshiyuki longtermhearingoutcomeafterretrosigmoidremovalofvestibularschwannoma
AT mizoguchimasahiro longtermhearingoutcomeafterretrosigmoidremovalofvestibularschwannoma
AT yoshimotokoji longtermhearingoutcomeafterretrosigmoidremovalofvestibularschwannoma
AT sasakitomio longtermhearingoutcomeafterretrosigmoidremovalofvestibularschwannoma