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Germinoma in Two Brothers: Case Report

We present a third reported case of intracranial germinomas occurring in two brothers. They underwent chemotherapy and radiotherapy after biopsy and are doing well for 10 years and 20 months, respectively. The pertinent literatures are reviewed, and the possible role of heredity in the pathogenesis...

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Detalles Bibliográficos
Autores principales: Nitta, Naoki, Fukami, Tadateru, Nozaki, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Neurosurgical Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508752/
https://www.ncbi.nlm.nih.gov/pubmed/24077266
http://dx.doi.org/10.2176/nmc.cr2012-0143
Descripción
Sumario:We present a third reported case of intracranial germinomas occurring in two brothers. They underwent chemotherapy and radiotherapy after biopsy and are doing well for 10 years and 20 months, respectively. The pertinent literatures are reviewed, and the possible role of heredity in the pathogenesis of familial occurrence of germinomas is discussed.