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Poised chromatin and bivalent domains facilitate the mitosis-to-meiosis transition in the male germline

BACKGROUND: The male germline transcriptome changes dramatically during the mitosis-to-meiosis transition to activate late spermatogenesis genes and to transiently suppress genes commonly expressed in somatic lineages and spermatogenesis progenitor cells, termed somatic/progenitor genes. RESULTS: Th...

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Detalles Bibliográficos
Autores principales: Sin, Ho-Su, Kartashov, Andrey V., Hasegawa, Kazuteru, Barski, Artem, Namekawa, Satoshi H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508805/
https://www.ncbi.nlm.nih.gov/pubmed/26198001
http://dx.doi.org/10.1186/s12915-015-0159-8