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MRC-5 fibroblast-conditioned medium influences multiple pathways regulating invasion, migration, proliferation, and apoptosis in hepatocellular carcinoma

BACKGROUND: Carcinoma associated fibroblasts (CAFs), an important component of tumor microenvironment, are capable of enhancing tumor cells invasion and migration through initiation of epithelial–mesenchymal transition (EMT). MRC-5 fibroblasts are one of the CAFs expressing alpha-smooth muscle actin...

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Detalles Bibliográficos
Autores principales:	Ding, Songming, Chen, Guoliang, Zhang, Wu, Xing, Chunyang, Xu, Xiao, Xie, Haiyang, Lu, Aili, Chen, Kangjie, Guo, Haijun, Ren, Zhigang, Zheng, Shusen, Zhou, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508812/ https://www.ncbi.nlm.nih.gov/pubmed/26198300 http://dx.doi.org/10.1186/s12967-015-0588-8

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