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The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells

Deubiquitinating enzymes (DUBs) negatively regulate protein ubiquitination and play an important role in diverse physiological processes, including mitotic division. The BRCC36 isopeptidase complex (BRISC) is a DUB that is specific for lysine 63–linked ubiquitin hydrolysis; however, its biological f...

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Detalles Bibliográficos
Autores principales:	Yan, Kaowen, Li, Li, Wang, Xiaojian, Hong, Ruisha, Zhang, Ying, Yang, Hua, Lin, Ming, Zhang, Sha, He, Qihua, Zheng, Duo, Tang, Jun, Yin, Yuxin, Shao, Genze
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508884/ https://www.ncbi.nlm.nih.gov/pubmed/26195665 http://dx.doi.org/10.1083/jcb.201503039

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