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ROCK1 and 2 differentially regulate actomyosin organization to drive cell and synaptic polarity

RhoGTPases organize the actin cytoskeleton to generate diverse polarities, from front–back polarity in migrating cells to dendritic spine morphology in neurons. For example, RhoA through its effector kinase, RhoA kinase (ROCK), activates myosin II to form actomyosin filament bundles and large adhesi...

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Detalles Bibliográficos
Autores principales:	Newell-Litwa, Karen A., Badoual, Mathilde, Asmussen, Hannelore, Patel, Heather, Whitmore, Leanna, Horwitz, Alan Rick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508895/ https://www.ncbi.nlm.nih.gov/pubmed/26169356 http://dx.doi.org/10.1083/jcb.201504046

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