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Synthesis of Cycloprodigiosin Identifies the Natural Isolate as a Scalemic Mixture

[Image: see text] The enantiomers of the natural product cycloprodigiosin were prepared using an expedient five-step synthetic sequence that takes advantage of a Schöllkopf–Barton–Zard (SBZ) pyrrole annulation with a chiral isocyanoacetate and a nitrocyclohexene derivative. Using chiral HPLC and X-r...

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Detalles Bibliográficos
Autores principales:	Johnson, Rebecca E., de Rond, Tristan, Lindsay, Vincent N. G., Keasling, Jay D., Sarpong, Richmond
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2015
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509414/ https://www.ncbi.nlm.nih.gov/pubmed/26114660 http://dx.doi.org/10.1021/acs.orglett.5b01527

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