Inside-out Ca(2+) signalling prompted by STIM1 conformational switch

Store-operated Ca(2+) entry mediated by STIM1 and ORAI1 constitutes one of the major Ca(2+) entry routes in mammalian cells. The molecular choreography of STIM1–ORAI1 coupling is initiated by endoplasmic reticulum (ER) Ca(2+) store depletion with subsequent oligomerization of the STIM1 ER-luminal do...

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Detalles Bibliográficos
Autores principales: Ma, Guolin, Wei, Ming, He, Lian, Liu, Chongxu, Wu, Bo, Zhang, Shenyuan L., Jing, Ji, Liang, Xiaowen, Senes, Alessandro, Tan, Peng, Li, Siwei, Sun, Aomin, Bi, Yunchen, Zhong, Ling, Si, Hongjiang, Shen, Yuequan, Li, Minyong, Lee, Mi-Sun, Zhou, Weibin, Wang, Junfeng, Wang, Youjun, Zhou, Yubin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509486/
https://www.ncbi.nlm.nih.gov/pubmed/26184105
http://dx.doi.org/10.1038/ncomms8826

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