A genital tract peptide epitope vaccine targeting TLR-2 efficiently induces local and systemic CD8(+) T cells and protects against herpes simplex virus type 2 challenge

The next generation of needle-free mucosal vaccines is being rationally designed according to rules that govern the way in which the epitopes are recognized by and stimulate the genital mucosal immune system. We hypothesized that synthetic peptide epitopes extended with an agonist of Toll-like recep...

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Detalles Bibliográficos
Autores principales: Zhang, X, Chentoufi, A A, Dasgupta, G, Nesburn, A B, Wu, M, Zhu, X, Carpenter, D, Wechsler, S L, You, S, BenMohamed, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: © Society for Mucosal Immunology. Published by Elsevier Inc. 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509510/
https://www.ncbi.nlm.nih.gov/pubmed/19129756
http://dx.doi.org/10.1038/mi.2008.81

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