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Role of apolipoprotein E in neurodegenerative diseases
Apolipoprotein E (APOE) is a lipid-transport protein abundantly expressed in most neurons in the central nervous system. APOE-dependent alterations of the endocytic pathway can affect different functions. APOE binds to cell-surface receptors to deliver lipids and to the hydrophobic amyloid-β peptide...
Autores principales: | Giau, Vo Van, Bagyinszky, Eva, An, Seong Soo A, Kim, Sang Yun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509527/ https://www.ncbi.nlm.nih.gov/pubmed/26213471 http://dx.doi.org/10.2147/NDT.S84266 |
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