Cargando…

Downregulation of miR203 induces overexpression of PIK3CA and predicts poor prognosis of gastric cancer patients

BACKGROUND: Despite advances in clinical therapies and technologies, the prognosis for patients with gastric cancer is still poor. The aim of this study is to investigate new predictive markers for prognosis of gastric cancer. METHODS: In this study, we evaluated the expression pattern of PIK3CA in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liang, Min, Shi, Boyun, Liu, Jifang, He, Lu, Yi, Gao, Zhou, Lin, Yu, Guifang, Zhou, Xinke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509530/ https://www.ncbi.nlm.nih.gov/pubmed/26213461 http://dx.doi.org/10.2147/DDDT.S85525

Ejemplares similares

Highly frequent PIK3CA amplification is associated with poor prognosis in gastric cancer
por: Shi, Jing, et al.
Publicado: (2012)

miR-20b overexpression is predictive of poor prognosis in gastric cancer
por: Xue, Tong-min, et al.
Publicado: (2015)

Down-regulation of miR-203 induced by Helicobacter pylori infection promotes the proliferation and invasion of gastric cancer by targeting CASK
por: Zhou, Xiaoying, et al.
Publicado: (2014)

Downregulation of miR-484 is associated with poor prognosis and tumor progression of gastric cancer
por: Li, Ying, et al.
Publicado: (2020)

Reduced RCE1 expression predicts poor prognosis of colorectal carcinoma
por: Shi, Boyun, et al.
Publicado: (2017)

Overexpression of miR-210 is Associated with Poor Prognosis of Acute Myeloid Leukemia
por: Tang, Xiaoqiong, et al.
Publicado: (2015)

PIK3CA gene mutation associated with poor prognosis of lung adenocarcinoma
por: Zhang, Lina, et al.
Publicado: (2013)

Reduced miR-203 predicts metastasis and poor survival in esophageal carcinoma
por: He, Rongqi, et al.
Publicado: (2019)

Downregulation of SIRT6 is associated with poor prognosis in patients with non-small cell lung cancer
por: Zhu, Bojin, et al.
Publicado: (2018)

Prognostic significance of miR-203 and ZEB1 expression in early-stage hepatocellular carcinoma
por: Chen, Hongyuan, et al.
Publicado: (2021)

miR-10a overexpression aggravates renal ischemia–reperfusion injury associated with decreased PIK3CA expression
por: Xu, Dongsheng, et al.
Publicado: (2020)

Downregulation of MiR-30a is Associated with Poor Prognosis in Lung Cancer
por: Tang, Ruixue, et al.
Publicado: (2015)

MiR-497 downregulation contributes to the malignancy of pancreatic cancer and associates with a poor prognosis
por: Xu, Jianwei, et al.
Publicado: (2014)

Mutations of PIK3CA in gastric adenocarcinoma
por: Li, Vivian Sze Wing, et al.
Publicado: (2005)

PIK3CA exon 20 mutations are associated with poor prognosis in breast cancer patients
por: Mangone, Flavia R., et al.
Publicado: (2012)

Downregulated miR-383-5p contributes to the proliferation and migration of gastric cancer cells and is associated with poor prognosis
por: Wei, Chao, et al.
Publicado: (2019)

miR-4653-3p overexpression is associated with a poor prognosis of pancreatic ductal adenocarcinoma via HIPK2 downregulation
por: Hirabayashi, Kenichi, et al.
Publicado: (2022)

Downregulation of MiR-203a Disinhibits Bmi1 and Promotes Growth and Proliferation of Keratinocytes in Cholesteatoma
por: Zang, Jian, et al.
Publicado: (2018)

LncRNA WT1-AS Downregulates Survivin by Upregulating miR-203 in Papillary Thyroid Carcinoma
por: Le, Fei, et al.
Publicado: (2020)

ITPKA induces cell senescence, inhibits ovarian cancer tumorigenesis and can be downregulated by miR-203
por: Shaosheng, Wang, et al.
Publicado: (2021)

miR‐203 inhibits cell proliferation, invasion, and migration of non‐small‐cell lung cancer by downregulating RGS17
por: Chi, Yongbin, et al.
Publicado: (2017)

Trop2 is overexpressed in gastric cancer and predicts poor prognosis
por: Zhao, Wei, et al.
Publicado: (2015)

Posttranscriptional deregulation of Src due to aberrant miR34a and miR203 contributes to gastric cancer development
por: Hao, Qiang, et al.
Publicado: (2013)

Downregulation of PSCA promotes gastric cancer proliferation and is related to poor prognosis
por: Xu, Li-pu, et al.
Publicado: (2020)

Circular RNA hsa_circ_0110389 promotes gastric cancer progression through upregulating SORT1 via sponging miR-127-5p and miR-136-5p
por: Liang, Min, et al.
Publicado: (2021)

Analysis of the expression of D-dimer, CD147 and miR203 and their correlation in gastric cancer
por: Wu, Xiguo, et al.
Publicado: (2019)

Overexpression of LBH is associated with poor prognosis in human hepatocellular carcinoma
por: Chen, Jiewei, et al.
Publicado: (2018)

Downregulation of circulating exosomal miR-638 predicts poor prognosis in colon cancer patients
por: Yan, Shushan, et al.
Publicado: (2017)

Downregulation of serum exosomal miR‐320d predicts poor prognosis in hepatocellular carcinoma
por: Li, Wenxiao, et al.
Publicado: (2020)

Ezrin overexpression predicts the poor prognosis of gastric adenocarcinoma
por: Jin, Jingchun, et al.
Publicado: (2012)

Overexpression of DGKI in Gastric Cancer Predicts Poor Prognosis
por: Huang, Chao, et al.
Publicado: (2020)

MiR-203 downregulation is responsible for chemoresistance in human glioblastoma by promoting epithelial-mesenchymal transition via SNAI2
por: Liao, Hongzhan, et al.
Publicado: (2015)

Association between PIK3CA alteration and prognosis of gastric cancer patients: a meta-analysis
por: Li, Hua, et al.
Publicado: (2018)

Expression and significance of EBV, ARID1A and PIK3CA in gastric carcinoma
por: Zhou, Huan, et al.
Publicado: (2019)

MiR-203 acts as a radiosensitizer of gastric cancer cells by directly targeting ZEB1
por: Jiang, Ying, et al.
Publicado: (2019)

LOXL1-AS1 Drives The Progression Of Gastric Cancer Via Regulating miR-142-5p/PIK3CA Axis
por: Li, Ming, et al.
Publicado: (2019)

Downregulation of ALDOB is associated with poor prognosis of patients with gastric cancer
por: He, Jun, et al.
Publicado: (2016)

Epigenetic inactivation of the hsa-miR-203 in haematological malignancies
por: Chim, Chor Sang, et al.
Publicado: (2011)

miR-203 drives breast cancer cell differentiation
por: Martínez-Illescas, Nuria G., et al.
Publicado: (2023)

LncRNA UCA1 promotes tumor metastasis by inducing miR-203/ZEB2 axis in gastric cancer
por: Gong, Pihai, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_kg1e01kaa995ka7qsbbadd2rpv