Structural Characterization of the Chaetomium thermophilum TREX-2 Complex and its Interaction with the mRNA Nuclear Export Factor Mex67:Mtr2

The TREX-2 complex integrates mRNA nuclear export into the gene expression pathway and is based on a Sac3 scaffold to which Thp1, Sem1, Sus1, and Cdc31 bind. TREX-2 also binds the mRNA nuclear export factor, Mex67:Mtr2, through the Sac3 N-terminal region (Sac3N). Here, we characterize Chaetomium the...

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Detalles Bibliográficos
Autores principales: Dimitrova, Lyudmila, Valkov, Eugene, Aibara, Shintaro, Flemming, Dirk, McLaughlin, Stephen H., Hurt, Ed, Stewart, Murray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509546/
https://www.ncbi.nlm.nih.gov/pubmed/26051714
http://dx.doi.org/10.1016/j.str.2015.05.002

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