Cargando…
Large-Scale and Comprehensive Immune Profiling and Functional Analysis of Normal Human Aging
While many age-associated immune changes have been reported, a comprehensive set of metrics of immune aging is lacking. Here we report data from 243 healthy adults aged 40–97, for whom we measured clinical and functional parameters, serum cytokines, cytokines and gene expression in stimulated and un...
Autores principales: | Whiting, Chan C., Siebert, Janet, Newman, Aaron M., Du, Hong-wu, Alizadeh, Ash A., Goronzy, Jorg, Weyand, Cornelia M., Krishnan, Eswar, Fathman, C. Garrison, Maecker, Holden T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509650/ https://www.ncbi.nlm.nih.gov/pubmed/26197454 http://dx.doi.org/10.1371/journal.pone.0133627 |
Ejemplares similares
-
Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity
por: Li, Guangjin, et al.
Publicado: (2012) -
Immune Checkpoint Function of CD85j in CD8 T Cell Differentiation and Aging
por: Gustafson, Claire E., et al.
Publicado: (2017) -
Mass cytometry as a platform for the discovery of cellular biomarkers to guide effective rheumatic disease therapy
por: Nair, Nitya, et al.
Publicado: (2015) -
T-cell co-stimulatory pathways in autoimmunity
por: Goronzy, Jörg J, et al.
Publicado: (2008) -
Developments in the scientific understanding of rheumatoid arthritis
por: Goronzy, Jörg J, et al.
Publicado: (2009)