Enhancement of insulin-mediated rat muscle glucose uptake and microvascular perfusion by 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside

BACKGROUND: Insulin-induced microvascular recruitment is important for optimal muscle glucose uptake. 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR, an activator of AMP-activated protein kinase), can also induce microvascular recruitment, at doses that do not acutely activate glucose tr...

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Detalles Bibliográficos
Autores principales: Bradley, Eloise A, Zhang, Lei, Genders, Amanda J, Richards, Stephen M, Rattigan, Stephen, Keske, Michelle A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509722/
https://www.ncbi.nlm.nih.gov/pubmed/26194188
http://dx.doi.org/10.1186/s12933-015-0251-y

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