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A case of B-cell acute lymphoblastic leukemia in a child with Down syndrome bearing a t(2;12)(p12;p13) involving ETV6 and biallelic IGH@ rearrangements

BACKGROUND: Rearrangements involving ETV6 (12p13) are among the most common structural abnormalities in pediatric B-cell acute lymphoblastic leukemia (B-ALL) and involve numerous partner genes. Additionally, the t(8;14)(q11.2;q32), which can result in the placement of CEBPD (8q11.2) near the regulat...

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Detalles Bibliográficos
Autores principales:	Tirado, Carlos A., Shabsovich, David, Kim, Yeun, Traum, Peter, Pullarkat, Sheeja, Kallen, Michael, Rao, Nagesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509750/ https://www.ncbi.nlm.nih.gov/pubmed/26203356 http://dx.doi.org/10.1186/s40364-015-0036-1

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