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Prognostic models for alcoholic hepatitis
Alcoholic hepatitis (AH) is caused by acute inflammation of the liver in patients that consume excessive amounts of alcohol, usually in a background of cirrhosis. AH can range from mild to severe, life threatening disease with a high rate of short and long-term mortality. Prognostic models have been...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509754/ https://www.ncbi.nlm.nih.gov/pubmed/26203357 http://dx.doi.org/10.1186/s40364-015-0046-z |
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author | Rahimi, Erik Pan, Jen-Jung |
author_facet | Rahimi, Erik Pan, Jen-Jung |
author_sort | Rahimi, Erik |
collection | PubMed |
description | Alcoholic hepatitis (AH) is caused by acute inflammation of the liver in patients that consume excessive amounts of alcohol, usually in a background of cirrhosis. AH can range from mild to severe, life threatening disease with a high rate of short and long-term mortality. Prognostic models have been used to estimate mortality in order to identify those that may benefit from corticosteroids or pentoxifylline. This review focuses on the different prognostic models proposed. While limitations of the prognostic models exist, combining models may be beneficial in order to identify responders to therapy versus non-responders. |
format | Online Article Text |
id | pubmed-4509754 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-45097542015-07-23 Prognostic models for alcoholic hepatitis Rahimi, Erik Pan, Jen-Jung Biomark Res Review Alcoholic hepatitis (AH) is caused by acute inflammation of the liver in patients that consume excessive amounts of alcohol, usually in a background of cirrhosis. AH can range from mild to severe, life threatening disease with a high rate of short and long-term mortality. Prognostic models have been used to estimate mortality in order to identify those that may benefit from corticosteroids or pentoxifylline. This review focuses on the different prognostic models proposed. While limitations of the prognostic models exist, combining models may be beneficial in order to identify responders to therapy versus non-responders. BioMed Central 2015-07-21 /pmc/articles/PMC4509754/ /pubmed/26203357 http://dx.doi.org/10.1186/s40364-015-0046-z Text en © Rahimi and Pan. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Rahimi, Erik Pan, Jen-Jung Prognostic models for alcoholic hepatitis |
title | Prognostic models for alcoholic hepatitis |
title_full | Prognostic models for alcoholic hepatitis |
title_fullStr | Prognostic models for alcoholic hepatitis |
title_full_unstemmed | Prognostic models for alcoholic hepatitis |
title_short | Prognostic models for alcoholic hepatitis |
title_sort | prognostic models for alcoholic hepatitis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509754/ https://www.ncbi.nlm.nih.gov/pubmed/26203357 http://dx.doi.org/10.1186/s40364-015-0046-z |
work_keys_str_mv | AT rahimierik prognosticmodelsforalcoholichepatitis AT panjenjung prognosticmodelsforalcoholichepatitis |