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The Orphan Nuclear Receptor TLX Is an Enhancer of STAT1-Mediated Transcription and Immunity to Toxoplasma gondii

The protozoan parasite, Toxoplasma, like many intracellular pathogens, suppresses interferon gamma (IFN-γ)-induced signal transducer and activator of transcription 1 (STAT1) activity. We exploited this well-defined host–pathogen interaction as the basis for a high-throughput screen, identifying nine...

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Detalles Bibliográficos
Autores principales:	Beiting, Daniel P., Hidano, Shinya, Baggs, Julie E., Geskes, Jeanne M., Fang, Qun, Wherry, E. John, Hunter, Christopher A., Roos, David S., Cherry, Sara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509904/ https://www.ncbi.nlm.nih.gov/pubmed/26196739 http://dx.doi.org/10.1371/journal.pbio.1002200

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