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Molecular and genetic aspects of odontogenic tumors: a review

Odontogenic tumors contain a heterogeneous collection of lesions that are categorized from hamartomas to benign and malignant neoplasms of inconstant aggressiveness. Odontogenic tumors are usually extraordinary with assessed frequency of short of 0.5 cases/100,000 population for every year. The lesi...

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Autores principales: Garg, Kavita, Chandra, Shaleen, Raj, Vineet, Fareed, Wamiq, Zafar, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509946/
https://www.ncbi.nlm.nih.gov/pubmed/26221475
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author Garg, Kavita
Chandra, Shaleen
Raj, Vineet
Fareed, Wamiq
Zafar, Muhammad
author_facet Garg, Kavita
Chandra, Shaleen
Raj, Vineet
Fareed, Wamiq
Zafar, Muhammad
author_sort Garg, Kavita
collection PubMed
description Odontogenic tumors contain a heterogeneous collection of lesions that are categorized from hamartomas to benign and malignant neoplasms of inconstant aggressiveness. Odontogenic tumors are usually extraordinary with assessed frequency of short of 0.5 cases/100,000 population for every year. The lesions such as odontogenic tumors are inferred from the components of the tooth-structuring contraption. They are discovered solely inside the maxillary and mandibular bones. This audit speaks to experiences and cooperation of the molecular and genetic variations connected to the development and movement of odontogenic tumors which incorporate oncogenes, tumor-silencer genes, APC gene, retinoblastoma genes, DNA repair genes, onco-viruses, development components, telomerase, cell cycle controllers, apoptosis-related elements, and regulators/conttrollers of tooth development. The reasonable and better understanding of the molecular components may prompt new ideas for their detection and administrating a better prognosis of odontogenic tumors.
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spelling pubmed-45099462015-07-28 Molecular and genetic aspects of odontogenic tumors: a review Garg, Kavita Chandra, Shaleen Raj, Vineet Fareed, Wamiq Zafar, Muhammad Iran J Basic Med Sci Review Article Odontogenic tumors contain a heterogeneous collection of lesions that are categorized from hamartomas to benign and malignant neoplasms of inconstant aggressiveness. Odontogenic tumors are usually extraordinary with assessed frequency of short of 0.5 cases/100,000 population for every year. The lesions such as odontogenic tumors are inferred from the components of the tooth-structuring contraption. They are discovered solely inside the maxillary and mandibular bones. This audit speaks to experiences and cooperation of the molecular and genetic variations connected to the development and movement of odontogenic tumors which incorporate oncogenes, tumor-silencer genes, APC gene, retinoblastoma genes, DNA repair genes, onco-viruses, development components, telomerase, cell cycle controllers, apoptosis-related elements, and regulators/conttrollers of tooth development. The reasonable and better understanding of the molecular components may prompt new ideas for their detection and administrating a better prognosis of odontogenic tumors. Mashhad University of Medical Sciences 2015-06 /pmc/articles/PMC4509946/ /pubmed/26221475 Text en Copyright: © Iranian Journal of Basic Medical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Garg, Kavita
Chandra, Shaleen
Raj, Vineet
Fareed, Wamiq
Zafar, Muhammad
Molecular and genetic aspects of odontogenic tumors: a review
title Molecular and genetic aspects of odontogenic tumors: a review
title_full Molecular and genetic aspects of odontogenic tumors: a review
title_fullStr Molecular and genetic aspects of odontogenic tumors: a review
title_full_unstemmed Molecular and genetic aspects of odontogenic tumors: a review
title_short Molecular and genetic aspects of odontogenic tumors: a review
title_sort molecular and genetic aspects of odontogenic tumors: a review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509946/
https://www.ncbi.nlm.nih.gov/pubmed/26221475
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