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Heterozygosis deficit of polymorphic markers linked to the β-globin gene cluster region in the Iranian population

OBJECTIVE(S): Iran is considered as one of the high-prevalence areas for β-thalassemia with a rate of about 10% carrier frequency. Molecular diagnosis of the disease is performed both by direct sequencing and indirectly by the use of polymorphic markers present in the beta globin gene cluster. Howev...

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Detalles Bibliográficos
Autores principales: Moradi, Tahereh, Vallian, Reihaneh, Fazeli, Zahra, Haghighatnia, Asieh, Vallian, Sadeq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509952/
https://www.ncbi.nlm.nih.gov/pubmed/26229579

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