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Development of RNA aptamers as molecular probes for HER2(+) breast cancer study using cell-SELEX

OBJECTIVE(S): Development of molecules that specifically recognize cancer cells is one of the major areas in cancer research. Human epidermal growth factor receptor 2 (HER2) is specifically expressed on the surface of breast cancer cells. HER2 is associated with an aggressive phenotype and poor prog...

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Detalles Bibliográficos
Autores principales: Moosavian, Seyedeh Alia, Jaafari, Mahmoud Reza, Taghdisi, Seyed Mohammad, Mosaffa, Fatemeh, Badiee, Ali, Abnous, Khalil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509953/
https://www.ncbi.nlm.nih.gov/pubmed/26221481