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Genome-wide analysis of translational efficiency reveals distinct but overlapping functions of yeast DEAD-box RNA helicases Ded1 and eIF4A

DEAD-box RNA helicases eIF4A and Ded1 are believed to promote translation initiation by resolving mRNA secondary structures that impede ribosome attachment at the mRNA 5′ end or subsequent scanning of the 5′ UTR, but whether they perform unique or overlapping functions in vivo is poorly understood....

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Detalles Bibliográficos
Autores principales:	Sen, Neelam Dabas, Zhou, Fujun, Ingolia, Nicholas T., Hinnebusch, Alan G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510003/ https://www.ncbi.nlm.nih.gov/pubmed/26122911 http://dx.doi.org/10.1101/gr.191601.115

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