Comparative secretome analysis of rat stomach under different nutritional status

The fact that gastric surgery is at the moment the most effective treatment to fight against obesity highlights the relevance of gastric derived proteins as potential targets to treat this pathology. Taking advantage of a previously established gastric explant model for endocrine studies, the proteo...

Descripción completa

Detalles Bibliográficos
Autores principales: Senin, Lucia L., Roca-Rivada, Arturo, Castelao, Cecilia, Alonso, Jana, Folgueira, Cintia, Casanueva, Felipe F., Pardo, Maria, Seoane, Luisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Data Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510049/
https://www.ncbi.nlm.nih.gov/pubmed/26217719
http://dx.doi.org/10.1016/j.dib.2015.01.002
_version_ 1782382109847977984
author Senin, Lucia L.
Roca-Rivada, Arturo
Castelao, Cecilia
Alonso, Jana
Folgueira, Cintia
Casanueva, Felipe F.
Pardo, Maria
Seoane, Luisa M.
author_facet Senin, Lucia L.
Roca-Rivada, Arturo
Castelao, Cecilia
Alonso, Jana
Folgueira, Cintia
Casanueva, Felipe F.
Pardo, Maria
Seoane, Luisa M.
author_sort Senin, Lucia L.
collection PubMed
description The fact that gastric surgery is at the moment the most effective treatment to fight against obesity highlights the relevance of gastric derived proteins as potential targets to treat this pathology. Taking advantage of a previously established gastric explant model for endocrine studies, the proteomic analysis of gastric secretome was performed. To validate this gastric explant system for proteomic analysis, the identification of ghrelin, a classical gastric derived peptide, was performed by MS. In addition, the differential analysis of gastric secretomes under differential nutritional status (control feeding vs fasting vs re-feeding) was performed. The MS identified proteins are showed in the present manuscript. The data supplied in this article is related to the research article entitled “Comparative secretome analysis of rat stomach under different nutritional status” [1].
format Online
Article
Text
id pubmed-4510049
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-45100492015-07-27 Comparative secretome analysis of rat stomach under different nutritional status Senin, Lucia L. Roca-Rivada, Arturo Castelao, Cecilia Alonso, Jana Folgueira, Cintia Casanueva, Felipe F. Pardo, Maria Seoane, Luisa M. Data Brief Data Article The fact that gastric surgery is at the moment the most effective treatment to fight against obesity highlights the relevance of gastric derived proteins as potential targets to treat this pathology. Taking advantage of a previously established gastric explant model for endocrine studies, the proteomic analysis of gastric secretome was performed. To validate this gastric explant system for proteomic analysis, the identification of ghrelin, a classical gastric derived peptide, was performed by MS. In addition, the differential analysis of gastric secretomes under differential nutritional status (control feeding vs fasting vs re-feeding) was performed. The MS identified proteins are showed in the present manuscript. The data supplied in this article is related to the research article entitled “Comparative secretome analysis of rat stomach under different nutritional status” [1]. Elsevier 2015-02-13 /pmc/articles/PMC4510049/ /pubmed/26217719 http://dx.doi.org/10.1016/j.dib.2015.01.002 Text en © 2015 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Data Article
Senin, Lucia L.
Roca-Rivada, Arturo
Castelao, Cecilia
Alonso, Jana
Folgueira, Cintia
Casanueva, Felipe F.
Pardo, Maria
Seoane, Luisa M.
Comparative secretome analysis of rat stomach under different nutritional status
title Comparative secretome analysis of rat stomach under different nutritional status
title_full Comparative secretome analysis of rat stomach under different nutritional status
title_fullStr Comparative secretome analysis of rat stomach under different nutritional status
title_full_unstemmed Comparative secretome analysis of rat stomach under different nutritional status
title_short Comparative secretome analysis of rat stomach under different nutritional status
title_sort comparative secretome analysis of rat stomach under different nutritional status
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510049/
https://www.ncbi.nlm.nih.gov/pubmed/26217719
http://dx.doi.org/10.1016/j.dib.2015.01.002
work_keys_str_mv AT seninlucial comparativesecretomeanalysisofratstomachunderdifferentnutritionalstatus
AT rocarivadaarturo comparativesecretomeanalysisofratstomachunderdifferentnutritionalstatus
AT castelaocecilia comparativesecretomeanalysisofratstomachunderdifferentnutritionalstatus
AT alonsojana comparativesecretomeanalysisofratstomachunderdifferentnutritionalstatus
AT folgueiracintia comparativesecretomeanalysisofratstomachunderdifferentnutritionalstatus
AT casanuevafelipef comparativesecretomeanalysisofratstomachunderdifferentnutritionalstatus
AT pardomaria comparativesecretomeanalysisofratstomachunderdifferentnutritionalstatus
AT seoaneluisam comparativesecretomeanalysisofratstomachunderdifferentnutritionalstatus

Ejemplares similares