Cargando…

Data in support of enhancing metabolomics research through data mining

Metabolomics research has evolved considerably, particularly during the last decade. Over the course of this evolution, the interest in this ‘omic’ discipline is now more evident than ever. However, the future of metabolomics will depend on its capability to find biomarkers. For that reason, data mi...

Descripción completa

Detalles Bibliográficos
Autores principales: Martínez-Arranz, Ibon, Mayo, Rebeca, Pérez-Cormenzana, Miriam, Mincholé, Itziar, Salazar, Lorena, Alonso, Cristina, Mato, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510074/
https://www.ncbi.nlm.nih.gov/pubmed/26217737
http://dx.doi.org/10.1016/j.dib.2015.02.008
_version_ 1782382115489316864
author Martínez-Arranz, Ibon
Mayo, Rebeca
Pérez-Cormenzana, Miriam
Mincholé, Itziar
Salazar, Lorena
Alonso, Cristina
Mato, José M.
author_facet Martínez-Arranz, Ibon
Mayo, Rebeca
Pérez-Cormenzana, Miriam
Mincholé, Itziar
Salazar, Lorena
Alonso, Cristina
Mato, José M.
author_sort Martínez-Arranz, Ibon
collection PubMed
description Metabolomics research has evolved considerably, particularly during the last decade. Over the course of this evolution, the interest in this ‘omic’ discipline is now more evident than ever. However, the future of metabolomics will depend on its capability to find biomarkers. For that reason, data mining constitutes a challenging task in metabolomics workflow. This work has been designed in support of the research article entitled “Enhancing metabolomics research through data mining”, which proposed a methodological data handling guideline. An aging research in healthy population was used as a guiding thread to illustrate this process. Here we provide a further interpretation of the obtained statistical results. We also focused on the importance of graphical visualization tools as a clue to understand the most common univariate and multivariate data analyses applied in metabolomics.
format Online
Article
Text
id pubmed-4510074
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-45100742015-07-27 Data in support of enhancing metabolomics research through data mining Martínez-Arranz, Ibon Mayo, Rebeca Pérez-Cormenzana, Miriam Mincholé, Itziar Salazar, Lorena Alonso, Cristina Mato, José M. Data Brief Data Article Metabolomics research has evolved considerably, particularly during the last decade. Over the course of this evolution, the interest in this ‘omic’ discipline is now more evident than ever. However, the future of metabolomics will depend on its capability to find biomarkers. For that reason, data mining constitutes a challenging task in metabolomics workflow. This work has been designed in support of the research article entitled “Enhancing metabolomics research through data mining”, which proposed a methodological data handling guideline. An aging research in healthy population was used as a guiding thread to illustrate this process. Here we provide a further interpretation of the obtained statistical results. We also focused on the importance of graphical visualization tools as a clue to understand the most common univariate and multivariate data analyses applied in metabolomics. Elsevier 2015-02-27 /pmc/articles/PMC4510074/ /pubmed/26217737 http://dx.doi.org/10.1016/j.dib.2015.02.008 Text en © 2015 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Data Article
Martínez-Arranz, Ibon
Mayo, Rebeca
Pérez-Cormenzana, Miriam
Mincholé, Itziar
Salazar, Lorena
Alonso, Cristina
Mato, José M.
Data in support of enhancing metabolomics research through data mining
title Data in support of enhancing metabolomics research through data mining
title_full Data in support of enhancing metabolomics research through data mining
title_fullStr Data in support of enhancing metabolomics research through data mining
title_full_unstemmed Data in support of enhancing metabolomics research through data mining
title_short Data in support of enhancing metabolomics research through data mining
title_sort data in support of enhancing metabolomics research through data mining
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510074/
https://www.ncbi.nlm.nih.gov/pubmed/26217737
http://dx.doi.org/10.1016/j.dib.2015.02.008
work_keys_str_mv AT martinezarranzibon datainsupportofenhancingmetabolomicsresearchthroughdatamining
AT mayorebeca datainsupportofenhancingmetabolomicsresearchthroughdatamining
AT perezcormenzanamiriam datainsupportofenhancingmetabolomicsresearchthroughdatamining
AT mincholeitziar datainsupportofenhancingmetabolomicsresearchthroughdatamining
AT salazarlorena datainsupportofenhancingmetabolomicsresearchthroughdatamining
AT alonsocristina datainsupportofenhancingmetabolomicsresearchthroughdatamining
AT matojosem datainsupportofenhancingmetabolomicsresearchthroughdatamining