Cargando…

Improving survival after endometrial cancer: the big picture

To improve survival in women with endometrial cancer, we need to look at the "big picture" beyond initial treatment. Although the majority of women will be diagnosed with early stage disease and are cured with surgery alone, there is a subgroup of women with advanced and high-risk early st...

Descripción completa

Detalles Bibliográficos
Autor principal: Kwon, Janice S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510340/
https://www.ncbi.nlm.nih.gov/pubmed/26197859
http://dx.doi.org/10.3802/jgo.2015.26.3.227
_version_ 1782382146649849856
author Kwon, Janice S.
author_facet Kwon, Janice S.
author_sort Kwon, Janice S.
collection PubMed
description To improve survival in women with endometrial cancer, we need to look at the "big picture" beyond initial treatment. Although the majority of women will be diagnosed with early stage disease and are cured with surgery alone, there is a subgroup of women with advanced and high-risk early stage disease whose life expectancy may be prolonged with the addition of chemotherapy. Immunohistochemistry will help to identify those women with Lynch syndrome who will benefit from more frequent colorectal cancer surveillance and genetic counseling. If they happen to be diagnosed with colorectal cancer, this information has an important therapeutic implication. And finally, because the majority of women will survive their diagnosis of endometrial cancer, they remain at risk for breast and colorectal cancer, so these women should be counselled about screening for these cancers. These three interventions will contribute to improving the overall survival of women with endometrial cancer.
format Online
Article
Text
id pubmed-4510340
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology
record_format MEDLINE/PubMed
spelling pubmed-45103402015-07-27 Improving survival after endometrial cancer: the big picture Kwon, Janice S. J Gynecol Oncol Review Article To improve survival in women with endometrial cancer, we need to look at the "big picture" beyond initial treatment. Although the majority of women will be diagnosed with early stage disease and are cured with surgery alone, there is a subgroup of women with advanced and high-risk early stage disease whose life expectancy may be prolonged with the addition of chemotherapy. Immunohistochemistry will help to identify those women with Lynch syndrome who will benefit from more frequent colorectal cancer surveillance and genetic counseling. If they happen to be diagnosed with colorectal cancer, this information has an important therapeutic implication. And finally, because the majority of women will survive their diagnosis of endometrial cancer, they remain at risk for breast and colorectal cancer, so these women should be counselled about screening for these cancers. These three interventions will contribute to improving the overall survival of women with endometrial cancer. Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology 2015-07 2015-07-08 /pmc/articles/PMC4510340/ /pubmed/26197859 http://dx.doi.org/10.3802/jgo.2015.26.3.227 Text en Copyright © 2015. Asian Society of Gynecologic Oncology, Korean Society of Gynecologic Oncology http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Kwon, Janice S.
Improving survival after endometrial cancer: the big picture
title Improving survival after endometrial cancer: the big picture
title_full Improving survival after endometrial cancer: the big picture
title_fullStr Improving survival after endometrial cancer: the big picture
title_full_unstemmed Improving survival after endometrial cancer: the big picture
title_short Improving survival after endometrial cancer: the big picture
title_sort improving survival after endometrial cancer: the big picture
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510340/
https://www.ncbi.nlm.nih.gov/pubmed/26197859
http://dx.doi.org/10.3802/jgo.2015.26.3.227
work_keys_str_mv AT kwonjanices improvingsurvivalafterendometrialcancerthebigpicture