Cargando…

24-hour human urine and serum profiles of bisphenol A following ingestion in soup: Individual pharmacokinetic data and emographics

Here we present data to evaluate potential absorption of Bisphenol A through non-metabolizing tissues of the upper digestive tract. Concurrent serum and urine concentrations of d6-BPA, and its glucuronide and sulfate conjugates, were measured over a 24 h period in 10 adult male volunteers following...

Descripción completa

Detalles Bibliográficos
Autores principales: Teeguarden, Justin G., Twaddle, Nathan C., Churchwell, Mona I., Yang, Xiaoxia, Fisher, Jeffrey W., Seryak, Liesel M., Doerge, Daniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510366/
https://www.ncbi.nlm.nih.gov/pubmed/26217767
http://dx.doi.org/10.1016/j.dib.2015.03.002
_version_ 1782382152559624192
author Teeguarden, Justin G.
Twaddle, Nathan C.
Churchwell, Mona I.
Yang, Xiaoxia
Fisher, Jeffrey W.
Seryak, Liesel M.
Doerge, Daniel R.
author_facet Teeguarden, Justin G.
Twaddle, Nathan C.
Churchwell, Mona I.
Yang, Xiaoxia
Fisher, Jeffrey W.
Seryak, Liesel M.
Doerge, Daniel R.
author_sort Teeguarden, Justin G.
collection PubMed
description Here we present data to evaluate potential absorption of Bisphenol A through non-metabolizing tissues of the upper digestive tract. Concurrent serum and urine concentrations of d6-BPA, and its glucuronide and sulfate conjugates, were measured over a 24 h period in 10 adult male volunteers following ingestion of 30 μg d6-BPA/kg body weight in soup. The pharmacokinetic behavior of BPA and its metabolites in this cohort (rapid absorption, complete elimination, evidence against sublingual absorption) was reported. This Data in Brief article contains the corresponding individual pharmacokinetic data, reports the demographics of the cohort and provides additional details related to the analytical methods employed and is related to [4].
format Online
Article
Text
id pubmed-4510366
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-45103662015-07-27 24-hour human urine and serum profiles of bisphenol A following ingestion in soup: Individual pharmacokinetic data and emographics Teeguarden, Justin G. Twaddle, Nathan C. Churchwell, Mona I. Yang, Xiaoxia Fisher, Jeffrey W. Seryak, Liesel M. Doerge, Daniel R. Data Brief Data Article Here we present data to evaluate potential absorption of Bisphenol A through non-metabolizing tissues of the upper digestive tract. Concurrent serum and urine concentrations of d6-BPA, and its glucuronide and sulfate conjugates, were measured over a 24 h period in 10 adult male volunteers following ingestion of 30 μg d6-BPA/kg body weight in soup. The pharmacokinetic behavior of BPA and its metabolites in this cohort (rapid absorption, complete elimination, evidence against sublingual absorption) was reported. This Data in Brief article contains the corresponding individual pharmacokinetic data, reports the demographics of the cohort and provides additional details related to the analytical methods employed and is related to [4]. Elsevier 2015-03-17 /pmc/articles/PMC4510366/ /pubmed/26217767 http://dx.doi.org/10.1016/j.dib.2015.03.002 Text en http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Data Article
Teeguarden, Justin G.
Twaddle, Nathan C.
Churchwell, Mona I.
Yang, Xiaoxia
Fisher, Jeffrey W.
Seryak, Liesel M.
Doerge, Daniel R.
24-hour human urine and serum profiles of bisphenol A following ingestion in soup: Individual pharmacokinetic data and emographics
title 24-hour human urine and serum profiles of bisphenol A following ingestion in soup: Individual pharmacokinetic data and emographics
title_full 24-hour human urine and serum profiles of bisphenol A following ingestion in soup: Individual pharmacokinetic data and emographics
title_fullStr 24-hour human urine and serum profiles of bisphenol A following ingestion in soup: Individual pharmacokinetic data and emographics
title_full_unstemmed 24-hour human urine and serum profiles of bisphenol A following ingestion in soup: Individual pharmacokinetic data and emographics
title_short 24-hour human urine and serum profiles of bisphenol A following ingestion in soup: Individual pharmacokinetic data and emographics
title_sort 24-hour human urine and serum profiles of bisphenol a following ingestion in soup: individual pharmacokinetic data and emographics
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510366/
https://www.ncbi.nlm.nih.gov/pubmed/26217767
http://dx.doi.org/10.1016/j.dib.2015.03.002
work_keys_str_mv AT teeguardenjusting 24hourhumanurineandserumprofilesofbisphenolafollowingingestioninsoupindividualpharmacokineticdataandemographics
AT twaddlenathanc 24hourhumanurineandserumprofilesofbisphenolafollowingingestioninsoupindividualpharmacokineticdataandemographics
AT churchwellmonai 24hourhumanurineandserumprofilesofbisphenolafollowingingestioninsoupindividualpharmacokineticdataandemographics
AT yangxiaoxia 24hourhumanurineandserumprofilesofbisphenolafollowingingestioninsoupindividualpharmacokineticdataandemographics
AT fisherjeffreyw 24hourhumanurineandserumprofilesofbisphenolafollowingingestioninsoupindividualpharmacokineticdataandemographics
AT seryaklieselm 24hourhumanurineandserumprofilesofbisphenolafollowingingestioninsoupindividualpharmacokineticdataandemographics
AT doergedanielr 24hourhumanurineandserumprofilesofbisphenolafollowingingestioninsoupindividualpharmacokineticdataandemographics