Data in support of quantification of pyrophosphate as a universal approach to determine polymerase activity and assay polymerase inhibitors

Characterization of synthetic oligonucleotides and quantification of primer extension mediated by a human translesion synthesis polymerase η (Pol η) over drug-induced DNA lesions in the presence on modified nucleotide analogs is described. Extent of primer extension for each reaction was monitored b...

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Detalles Bibliográficos
Autores principales: Malvezzi, S., Sturla, S.J., Tanasova, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Data Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510374/
https://www.ncbi.nlm.nih.gov/pubmed/26217754
http://dx.doi.org/10.1016/j.dib.2015.04.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510374/
https://www.ncbi.nlm.nih.gov/pubmed/26217754
http://dx.doi.org/10.1016/j.dib.2015.04.006

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