Cargando…
Data in support of quantification of pyrophosphate as a universal approach to determine polymerase activity and assay polymerase inhibitors
Characterization of synthetic oligonucleotides and quantification of primer extension mediated by a human translesion synthesis polymerase η (Pol η) over drug-induced DNA lesions in the presence on modified nucleotide analogs is described. Extent of primer extension for each reaction was monitored b...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510374/ https://www.ncbi.nlm.nih.gov/pubmed/26217754 http://dx.doi.org/10.1016/j.dib.2015.04.006 |