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Identification of Androgen Receptor Splice Variants in the Pten Deficient Murine Prostate Cancer Model

Androgen receptor (AR) variants are associated with resistance to anti androgen therapy both in human prostate cancer cell lines and clinical samples. These observations support the hypothesis that AR isoform accumulation is a consequence of selective therapeutic pressure on the full length AR. The...

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Detalles Bibliográficos
Autores principales: Liang, Mengmeng, Adisetiyo, Helty, Liu, Xiuqing, Liu, Ren, Gill, Parkash, Roy-Burman, Pradip, Jones, Jeremy O., Mulholland, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510390/
https://www.ncbi.nlm.nih.gov/pubmed/26196517
http://dx.doi.org/10.1371/journal.pone.0131232