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Identification of Androgen Receptor Splice Variants in the Pten Deficient Murine Prostate Cancer Model
Androgen receptor (AR) variants are associated with resistance to anti androgen therapy both in human prostate cancer cell lines and clinical samples. These observations support the hypothesis that AR isoform accumulation is a consequence of selective therapeutic pressure on the full length AR. The...
Autores principales: | Liang, Mengmeng, Adisetiyo, Helty, Liu, Xiuqing, Liu, Ren, Gill, Parkash, Roy-Burman, Pradip, Jones, Jeremy O., Mulholland, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510390/ https://www.ncbi.nlm.nih.gov/pubmed/26196517 http://dx.doi.org/10.1371/journal.pone.0131232 |
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