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Detection of First-Line Anti-Tuberculosis Drug Resistance Mutations by Allele-Specific Primer Extension on a Microsphere-Based Platform

BACKGROUND: Resistance of Mycobacterium tuberculosis to anti-tuberculosis (TB) drugs is almost exclusively due to spontaneous chromosomal mutations in target genes. Rapid detection of drug resistance to both first- and second-line anti-TB drugs has become a key component of TB control programs. Tech...

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Detalles Bibliográficos
Autores principales: Lee, Seung Heon, Choi, Hee Baeg, Yu, Sung Yul, Chang, Uck Jin, Kim, Chang Ki, Kim, Hee Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Laboratory Medicine 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510500/
https://www.ncbi.nlm.nih.gov/pubmed/26206684
http://dx.doi.org/10.3343/alm.2015.35.5.487