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Prediction of Links and Weights in Networks by Reliable Routes

Link prediction aims to uncover missing links or predict the emergence of future relationships from the current network structure. Plenty of algorithms have been developed for link prediction in unweighted networks, but only a few have been extended to weighted networks. In this paper, we present wh...

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Detalles Bibliográficos
Autores principales: Zhao, Jing, Miao, Lili, Yang, Jian, Fang, Haiyang, Zhang, Qian-Ming, Nie, Min, Holme, Petter, Zhou, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510530/
https://www.ncbi.nlm.nih.gov/pubmed/26198206
http://dx.doi.org/10.1038/srep12261
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author Zhao, Jing
Miao, Lili
Yang, Jian
Fang, Haiyang
Zhang, Qian-Ming
Nie, Min
Holme, Petter
Zhou, Tao
author_facet Zhao, Jing
Miao, Lili
Yang, Jian
Fang, Haiyang
Zhang, Qian-Ming
Nie, Min
Holme, Petter
Zhou, Tao
author_sort Zhao, Jing
collection PubMed
description Link prediction aims to uncover missing links or predict the emergence of future relationships from the current network structure. Plenty of algorithms have been developed for link prediction in unweighted networks, but only a few have been extended to weighted networks. In this paper, we present what we call a “reliable-route method” to extend unweighted local similarity indices to weighted ones. Using these indices, we can predict both the existence of links and their weights. Experiments on various real-world networks suggest that our reliable-route weighted resource-allocation index performs noticeably better than others with respect to weight prediction. For existence prediction it is either the highest or very close to the highest. Further analysis shows a strong positive correlation between the clustering coefficient and prediction accuracy. Finally, we apply our method to the prediction of missing protein-protein interactions and their confidence scores from known PPI networks. Once again, our reliable-route method shows the highest accuracy.
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spelling pubmed-45105302015-07-28 Prediction of Links and Weights in Networks by Reliable Routes Zhao, Jing Miao, Lili Yang, Jian Fang, Haiyang Zhang, Qian-Ming Nie, Min Holme, Petter Zhou, Tao Sci Rep Article Link prediction aims to uncover missing links or predict the emergence of future relationships from the current network structure. Plenty of algorithms have been developed for link prediction in unweighted networks, but only a few have been extended to weighted networks. In this paper, we present what we call a “reliable-route method” to extend unweighted local similarity indices to weighted ones. Using these indices, we can predict both the existence of links and their weights. Experiments on various real-world networks suggest that our reliable-route weighted resource-allocation index performs noticeably better than others with respect to weight prediction. For existence prediction it is either the highest or very close to the highest. Further analysis shows a strong positive correlation between the clustering coefficient and prediction accuracy. Finally, we apply our method to the prediction of missing protein-protein interactions and their confidence scores from known PPI networks. Once again, our reliable-route method shows the highest accuracy. Nature Publishing Group 2015-07-22 /pmc/articles/PMC4510530/ /pubmed/26198206 http://dx.doi.org/10.1038/srep12261 Text en Copyright © 2015, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Zhao, Jing
Miao, Lili
Yang, Jian
Fang, Haiyang
Zhang, Qian-Ming
Nie, Min
Holme, Petter
Zhou, Tao
Prediction of Links and Weights in Networks by Reliable Routes
title Prediction of Links and Weights in Networks by Reliable Routes
title_full Prediction of Links and Weights in Networks by Reliable Routes
title_fullStr Prediction of Links and Weights in Networks by Reliable Routes
title_full_unstemmed Prediction of Links and Weights in Networks by Reliable Routes
title_short Prediction of Links and Weights in Networks by Reliable Routes
title_sort prediction of links and weights in networks by reliable routes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510530/
https://www.ncbi.nlm.nih.gov/pubmed/26198206
http://dx.doi.org/10.1038/srep12261
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