Cell type specificity of tissue plasminogen activator in the mouse barrel cortex

We provide data in this article related to (C.C. Chen et al.,. Neurosci. Lett., 599 (2015) 152–157.) [1] where the expression of tissue plasminogen activator (tPA) is expressed by the whisker representation in the somatosensory cortex. Here, we provide immunocytochemistry data indicating that tPA is...

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Detalles Bibliográficos
Autores principales: Chu, Philip, Chen, Eric, Bajnath, Adesh, Brumberg, Joshua C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Data Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510555/
https://www.ncbi.nlm.nih.gov/pubmed/26217811
http://dx.doi.org/10.1016/j.dib.2015.06.008
Descripción
Sumario:We provide data in this article related to (C.C. Chen et al.,. Neurosci. Lett., 599 (2015) 152–157.) [1] where the expression of tissue plasminogen activator (tPA) is expressed by the whisker representation in the somatosensory cortex. Here, we provide immunocytochemistry data indicating that tPA is expressed by putative excitatory neurons as well as parvalbumin+ interneurons but not by somatostatin+ inhibitory interneurons. We also provide data showing that microglia do not normally express high levels of tPA, but upregulate their levels following cortical penetration with a recording electrode.

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