Cell type specificity of tissue plasminogen activator in the mouse barrel cortex

We provide data in this article related to (C.C. Chen et al.,. Neurosci. Lett., 599 (2015) 152–157.) [1] where the expression of tissue plasminogen activator (tPA) is expressed by the whisker representation in the somatosensory cortex. Here, we provide immunocytochemistry data indicating that tPA is...

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Detalles Bibliográficos
Autores principales: Chu, Philip, Chen, Eric, Bajnath, Adesh, Brumberg, Joshua C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Data Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510555/
https://www.ncbi.nlm.nih.gov/pubmed/26217811
http://dx.doi.org/10.1016/j.dib.2015.06.008
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author Chu, Philip
Chen, Eric
Bajnath, Adesh
Brumberg, Joshua C.
author_facet Chu, Philip
Chen, Eric
Bajnath, Adesh
Brumberg, Joshua C.
author_sort Chu, Philip
collection PubMed
description We provide data in this article related to (C.C. Chen et al.,. Neurosci. Lett., 599 (2015) 152–157.) [1] where the expression of tissue plasminogen activator (tPA) is expressed by the whisker representation in the somatosensory cortex. Here, we provide immunocytochemistry data indicating that tPA is expressed by putative excitatory neurons as well as parvalbumin+ interneurons but not by somatostatin+ inhibitory interneurons. We also provide data showing that microglia do not normally express high levels of tPA, but upregulate their levels following cortical penetration with a recording electrode.
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spelling pubmed-45105552015-07-27 Cell type specificity of tissue plasminogen activator in the mouse barrel cortex Chu, Philip Chen, Eric Bajnath, Adesh Brumberg, Joshua C. Data Brief Data Article We provide data in this article related to (C.C. Chen et al.,. Neurosci. Lett., 599 (2015) 152–157.) [1] where the expression of tissue plasminogen activator (tPA) is expressed by the whisker representation in the somatosensory cortex. Here, we provide immunocytochemistry data indicating that tPA is expressed by putative excitatory neurons as well as parvalbumin+ interneurons but not by somatostatin+ inhibitory interneurons. We also provide data showing that microglia do not normally express high levels of tPA, but upregulate their levels following cortical penetration with a recording electrode. Elsevier 2015-06-25 /pmc/articles/PMC4510555/ /pubmed/26217811 http://dx.doi.org/10.1016/j.dib.2015.06.008 Text en © 2015 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Data Article
Chu, Philip
Chen, Eric
Bajnath, Adesh
Brumberg, Joshua C.
Cell type specificity of tissue plasminogen activator in the mouse barrel cortex
title Cell type specificity of tissue plasminogen activator in the mouse barrel cortex
title_full Cell type specificity of tissue plasminogen activator in the mouse barrel cortex
title_fullStr Cell type specificity of tissue plasminogen activator in the mouse barrel cortex
title_full_unstemmed Cell type specificity of tissue plasminogen activator in the mouse barrel cortex
title_short Cell type specificity of tissue plasminogen activator in the mouse barrel cortex
title_sort cell type specificity of tissue plasminogen activator in the mouse barrel cortex
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510555/
https://www.ncbi.nlm.nih.gov/pubmed/26217811
http://dx.doi.org/10.1016/j.dib.2015.06.008
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