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Cryo-EM structure of Hepatitis C virus IRES bound to the human ribosome at 3.9-Å resolution
Hepatitis C virus (HCV), a widespread human pathogen, is dependent on a highly structured 5′-untranslated region of its mRNA, referred to as internal ribosome entry site (IRES), for the translation of all of its proteins. The HCV IRES initiates translation by directly binding to the small ribosomal...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Pub. Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510694/ https://www.ncbi.nlm.nih.gov/pubmed/26155016 http://dx.doi.org/10.1038/ncomms8646 |