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Recruitment of VPS33A to HOPS by VPS16 Is Required for Lysosome Fusion with Endosomes and Autophagosomes

The mammalian homotypic fusion and vacuole protein sorting (HOPS) complex is comprised of six subunits: VPS11, VPS16, VPS18, VPS39, VPS41 and the Sec1/Munc18 (SM) family member VPS33A. Human HOPS has been predicted to be a tethering complex required for fusion of intracellular compartments with lyso...

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Detalles Bibliográficos
Autores principales:	Wartosch, Lena, Günesdogan, Ufuk, Graham, Stephen C., Luzio, J. Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons A/S 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510706/ https://www.ncbi.nlm.nih.gov/pubmed/25783203 http://dx.doi.org/10.1111/tra.12283

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