Tetanus toxoid and CCL3 improve DC vaccines in mice and glioblastoma patients

Upon stimulation, dendritic cells (DCs) mature and migrate to draining lymph nodes to induce immune responses(1). As such, autologous DCs generated ex vivo have been pulsed with tumor antigens and injected back into patients as immunotherapy. While DC vaccines have shown limited promise in the treat...

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Detalles Bibliográficos
Autores principales: Mitchell, Duane A., Batich, Kristen A., Gunn, Michael D., Huang, Min-Nung, Sanchez-Perez, Luis, Nair, Smita K., Congdon, Kendra L., Reap, Elizabeth A., Archer, Gary E., Desjardins, Annick, Friedman, Allan H., Friedman, Henry S., Herndon, James E., Coan, April, McLendon, Roger E., Reardon, David A., Vredenburgh, James J., Bigner, Darell D., Sampson, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510871/
https://www.ncbi.nlm.nih.gov/pubmed/25762141
http://dx.doi.org/10.1038/nature14320

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