Tumor necrosis factor-α enhances voltage-gated Na(+) currents in primary culture of mouse cortical neurons

BACKGROUND: Previous studies showed that TNF-α could activate voltage-gated Na(+) channels (VGSCs) in the peripheral nervous system (PNS). Since TNF-α is implicated in many central nervous system (CNS) diseases, we examined potential effects of TNF-α on VGSCs in the CNS. METHODS: Effects of TNF-α (1...

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Detalles Bibliográficos
Autores principales: Chen, Weiqiang, Sheng, Jiangtao, Guo, Jingfang, Gao, Fenfei, Zhao, Xiangfeng, Dai, Jianping, Wang, Gefei, Li, Kangsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510892/
https://www.ncbi.nlm.nih.gov/pubmed/26112872
http://dx.doi.org/10.1186/s12974-015-0349-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510892/
https://www.ncbi.nlm.nih.gov/pubmed/26112872
http://dx.doi.org/10.1186/s12974-015-0349-x

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