Development of a Transgenic Mouse with R124H Human TGFBI Mutation Associated with Granular Corneal Dystrophy Type 2

PURPOSE: To investigate the phenotype and predisposing factors of a granular corneal dystrophy type 2 transgenic mouse model. METHODS: Human TGFBI cDNA with R124H mutation was used to make a transgenic mouse expressing human protein (TGFBI(R124H) mouse). Reverse transcription PCR (RT-PCR) was perfor...

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Detalles Bibliográficos
Autores principales: Yamazoe, Katsuya, Yoshida, Satoru, Yasuda, Miyuki, Hatou, Shin, Inagaki, Emi, Ogawa, Yoko, Tsubota, Kazuo, Shimmura, Shigeto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511001/
https://www.ncbi.nlm.nih.gov/pubmed/26197481
http://dx.doi.org/10.1371/journal.pone.0133397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511001/
https://www.ncbi.nlm.nih.gov/pubmed/26197481
http://dx.doi.org/10.1371/journal.pone.0133397

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