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Melatonin: a potential intervention for hepatic steatosis
Melatonin (N-acetyl-5-methoxytryptamine, MLT) is a neuroendocrine hormone, which is primarily synthesized by the pineal gland in vertebrates. Melatonin is a remarkable molecule with diverse biological and physiological actions and is involved in the regulation of various important functions such as...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511016/ https://www.ncbi.nlm.nih.gov/pubmed/26199093 http://dx.doi.org/10.1186/s12944-015-0081-7 |
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author | Sun, Hang Huang, Fang-fang Qu, Shen |
author_facet | Sun, Hang Huang, Fang-fang Qu, Shen |
author_sort | Sun, Hang |
collection | PubMed |
description | Melatonin (N-acetyl-5-methoxytryptamine, MLT) is a neuroendocrine hormone, which is primarily synthesized by the pineal gland in vertebrates. Melatonin is a remarkable molecule with diverse biological and physiological actions and is involved in the regulation of various important functions such as circadian rhythm, energy metabolism, the reproductive system, the cardiovascular system, and the neuropsychiatric system. It also plays a role in disease by having anti-neoplastic and anti-osteoarthritic effects among others. Recently, research has focused on the roles of melatonin in oxidative stress, lipid metabolism, and hepatic steatosis and its potential therapeutic roles. |
format | Online Article Text |
id | pubmed-4511016 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-45110162015-07-23 Melatonin: a potential intervention for hepatic steatosis Sun, Hang Huang, Fang-fang Qu, Shen Lipids Health Dis Review Melatonin (N-acetyl-5-methoxytryptamine, MLT) is a neuroendocrine hormone, which is primarily synthesized by the pineal gland in vertebrates. Melatonin is a remarkable molecule with diverse biological and physiological actions and is involved in the regulation of various important functions such as circadian rhythm, energy metabolism, the reproductive system, the cardiovascular system, and the neuropsychiatric system. It also plays a role in disease by having anti-neoplastic and anti-osteoarthritic effects among others. Recently, research has focused on the roles of melatonin in oxidative stress, lipid metabolism, and hepatic steatosis and its potential therapeutic roles. BioMed Central 2015-07-22 /pmc/articles/PMC4511016/ /pubmed/26199093 http://dx.doi.org/10.1186/s12944-015-0081-7 Text en © Sun et al. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Sun, Hang Huang, Fang-fang Qu, Shen Melatonin: a potential intervention for hepatic steatosis |
title | Melatonin: a potential intervention for hepatic steatosis |
title_full | Melatonin: a potential intervention for hepatic steatosis |
title_fullStr | Melatonin: a potential intervention for hepatic steatosis |
title_full_unstemmed | Melatonin: a potential intervention for hepatic steatosis |
title_short | Melatonin: a potential intervention for hepatic steatosis |
title_sort | melatonin: a potential intervention for hepatic steatosis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511016/ https://www.ncbi.nlm.nih.gov/pubmed/26199093 http://dx.doi.org/10.1186/s12944-015-0081-7 |
work_keys_str_mv | AT sunhang melatoninapotentialinterventionforhepaticsteatosis AT huangfangfang melatoninapotentialinterventionforhepaticsteatosis AT qushen melatoninapotentialinterventionforhepaticsteatosis |