Cargando…

Melatonin: a potential intervention for hepatic steatosis

Melatonin (N-acetyl-5-methoxytryptamine, MLT) is a neuroendocrine hormone, which is primarily synthesized by the pineal gland in vertebrates. Melatonin is a remarkable molecule with diverse biological and physiological actions and is involved in the regulation of various important functions such as...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Hang, Huang, Fang-fang, Qu, Shen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511016/
https://www.ncbi.nlm.nih.gov/pubmed/26199093
http://dx.doi.org/10.1186/s12944-015-0081-7
_version_ 1782382277893816320
author Sun, Hang
Huang, Fang-fang
Qu, Shen
author_facet Sun, Hang
Huang, Fang-fang
Qu, Shen
author_sort Sun, Hang
collection PubMed
description Melatonin (N-acetyl-5-methoxytryptamine, MLT) is a neuroendocrine hormone, which is primarily synthesized by the pineal gland in vertebrates. Melatonin is a remarkable molecule with diverse biological and physiological actions and is involved in the regulation of various important functions such as circadian rhythm, energy metabolism, the reproductive system, the cardiovascular system, and the neuropsychiatric system. It also plays a role in disease by having anti-neoplastic and anti-osteoarthritic effects among others. Recently, research has focused on the roles of melatonin in oxidative stress, lipid metabolism, and hepatic steatosis and its potential therapeutic roles.
format Online
Article
Text
id pubmed-4511016
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-45110162015-07-23 Melatonin: a potential intervention for hepatic steatosis Sun, Hang Huang, Fang-fang Qu, Shen Lipids Health Dis Review Melatonin (N-acetyl-5-methoxytryptamine, MLT) is a neuroendocrine hormone, which is primarily synthesized by the pineal gland in vertebrates. Melatonin is a remarkable molecule with diverse biological and physiological actions and is involved in the regulation of various important functions such as circadian rhythm, energy metabolism, the reproductive system, the cardiovascular system, and the neuropsychiatric system. It also plays a role in disease by having anti-neoplastic and anti-osteoarthritic effects among others. Recently, research has focused on the roles of melatonin in oxidative stress, lipid metabolism, and hepatic steatosis and its potential therapeutic roles. BioMed Central 2015-07-22 /pmc/articles/PMC4511016/ /pubmed/26199093 http://dx.doi.org/10.1186/s12944-015-0081-7 Text en © Sun et al. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Sun, Hang
Huang, Fang-fang
Qu, Shen
Melatonin: a potential intervention for hepatic steatosis
title Melatonin: a potential intervention for hepatic steatosis
title_full Melatonin: a potential intervention for hepatic steatosis
title_fullStr Melatonin: a potential intervention for hepatic steatosis
title_full_unstemmed Melatonin: a potential intervention for hepatic steatosis
title_short Melatonin: a potential intervention for hepatic steatosis
title_sort melatonin: a potential intervention for hepatic steatosis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511016/
https://www.ncbi.nlm.nih.gov/pubmed/26199093
http://dx.doi.org/10.1186/s12944-015-0081-7
work_keys_str_mv AT sunhang melatoninapotentialinterventionforhepaticsteatosis
AT huangfangfang melatoninapotentialinterventionforhepaticsteatosis
AT qushen melatoninapotentialinterventionforhepaticsteatosis