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Impact of the expression of thymidylate synthase and dihydropyrimidine dehydrogenase genes on survival in stage II/III gastric cancer

BACKGROUND: The efficacy of 5-fluorouracil (5FU)-based therapy, which remains the cornerstone of gastrointestinal cancer treatment, depends upon the expression of enzymes involved in pyrimidine metabolism, including thymidylate synthase (TS), dihydropyrimidine dehydrogenase (DPD), thymidine phosphor...

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Detalles Bibliográficos
Autores principales:	Sasako, Mitsuru, Terashima, Masanori, Ichikawa, Wataru, Ochiai, Atsushi, Kitada, Koji, Kurahashi, Issei, Sakuramoto, Shinichi, Katai, Hitoshi, Sano, Takeshi, Imamura, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Japan 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511074/ https://www.ncbi.nlm.nih.gov/pubmed/25112781 http://dx.doi.org/10.1007/s10120-014-0413-8

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