Generation of lentivirus-induced dendritic cells under GMP-compliant conditions for adaptive immune reconstitution against cytomegalovirus after stem cell transplantation

BACKGROUND: Reactivation of latent viruses such as human cytomegalovirus (HCMV) after allogeneic hematopoietic stem cell transplantation (HSCT) results in high morbidity and mortality. Effective immunization against HCMV shortly after allo-HSCT is an unmet clinical need due to delayed adaptive T cel...

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Detalles Bibliográficos
Autores principales: Sundarasetty, Bala Sai, Kloess, Stephan, Oberschmidt, Olaf, Naundorf, Sonja, Kuehlcke, Klaus, Daenthanasanmak, Anusara, Gerasch, Laura, Figueiredo, Constanca, Blasczyk, Rainer, Ruggiero, Eliana, Fronza, Raffaele, Schmidt, Manfred, von Kalle, Christof, Rothe, Michael, Ganser, Arnold, Koehl, Ulrike, Stripecke, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511080/
https://www.ncbi.nlm.nih.gov/pubmed/26198406
http://dx.doi.org/10.1186/s12967-015-0599-5

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