Cellular MicroRNA Let-7a Suppresses KSHV Replication through Targeting MAP4K4 Signaling Pathways

BACKGROUND: Kaposi’s sarcoma (KS)-associated herpesvirus (KSHV) is the etiologic agent of KS, the most common AIDS-related malignancy. The majority of KS tumor cells harbor latent KSHV virus but only a small percentage undergoes spontaneous lytic replication. Viral reactivation from latency is cruci...

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Detalles Bibliográficos
Autores principales: Tan, Xiaohua, Gao, Yuan, Nan, Yulong, Zhang, Jinxia, Di, Chunhong, Wang, Xiaobo, Lian, Fuzhi, Cao, Yifei, Hu, Yu, Xu, Liangwen, Ma, Haiyan, Hong, Yu, Liu, Tingjie, Wu, Yinyin, Xu, Xianrong, Yan, Yutao, Yang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511191/
https://www.ncbi.nlm.nih.gov/pubmed/26197270
http://dx.doi.org/10.1371/journal.pone.0132148

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