HDAC4 is required for inflammation-associated thermal hypersensitivity

Transcriptional alterations are characteristic of persistent pain states, but the key regulators remain elusive. HDAC4 is a transcriptional corepressor that has been linked to synaptic plasticity and neuronal excitability, mechanisms that may be involved in peripheral and central sensitization. Usin...

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Detalles Bibliográficos
Autores principales: Crow, Megan, Khovanov, Nikita, Kelleher, Jayne H., Sharma, Simone, Grant, Andrew D., Bogdanov, Yury, Wood, John N., McMahon, Stephen B., Denk, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2015
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511203/
https://www.ncbi.nlm.nih.gov/pubmed/25903105
http://dx.doi.org/10.1096/fj.14-264440

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