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Dimerization-driven degradation of C. elegans and human E proteins

E proteins are conserved regulators of growth and development. We show that the Caenorhabditis elegans E-protein helix–loop–helix-2 (HLH-2) functions as a homodimer in directing development and function of the anchor cell (AC) of the gonad, the critical organizer of uterine and vulval development. O...

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Detalles Bibliográficos
Autores principales: Sallee, Maria D., Greenwald, Iva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511211/
https://www.ncbi.nlm.nih.gov/pubmed/26159995
http://dx.doi.org/10.1101/gad.261917.115