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RNF17 blocks promiscuous activity of PIWI proteins in mouse testes

PIWI proteins and their associated piRNAs protect germ cells from the activity of mobile genetic elements. Two classes of piRNAs—primary and secondary—are defined by their mechanisms of biogenesis. Primary piRNAs are processed directly from transcripts of piRNA cluster loci, whereas secondary piRNAs...

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Detalles Bibliográficos
Autores principales:	Wasik, Kaja A., Tam, Oliver H., Knott, Simon R., Falciatori, Ilaria, Hammell, Molly, Vagin, Vasily V., Hannon, Gregory J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511215/ https://www.ncbi.nlm.nih.gov/pubmed/26115953 http://dx.doi.org/10.1101/gad.265215.115

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