Sphingosine 1 Phosphate at the Blood Brain Barrier: Can the Modulation of S1P Receptor 1 Influence the Response of Endothelial Cells and Astrocytes to Inflammatory Stimuli?

The ability of the Blood Brain Barrier (BBB) to maintain proper barrier functions, keeping an optimal environment for central nervous system (CNS) activity and regulating leukocytes’ access, can be affected in CNS diseases. Endothelial cells and astrocytes are the principal BBB cellular constituents...

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Detalles Bibliográficos
Autores principales: Spampinato, Simona F., Obermeier, Birgit, Cotleur, Anne, Love, Anna, Takeshita, Yukio, Sano, Yasuteru, Kanda, Takashi, Ransohoff, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511229/
https://www.ncbi.nlm.nih.gov/pubmed/26197437
http://dx.doi.org/10.1371/journal.pone.0133392

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