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Early markers of right heart involvement in regular smokers by Pocket Size Imaging Device

PURPOSE: To test the diagnostic power of Pocket Size Imaging Device (PSID) in detecting early signs of right heart (RH) involvement in regular smokers (RS) free of overt cardiac involvement. METHODS: One-hundred-forty-three regular smokers and 51 healthy controls, comparable for age and sex, underwe...

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Autores principales: Schiano-Lomoriello, Vincenzo, Esposito, Roberta, Santoro, Ciro, de Simone, Giovanni, Galderisi, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511232/
https://www.ncbi.nlm.nih.gov/pubmed/26201963
http://dx.doi.org/10.1186/s12947-015-0024-5
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author Schiano-Lomoriello, Vincenzo
Esposito, Roberta
Santoro, Ciro
de Simone, Giovanni
Galderisi, Maurizio
author_facet Schiano-Lomoriello, Vincenzo
Esposito, Roberta
Santoro, Ciro
de Simone, Giovanni
Galderisi, Maurizio
author_sort Schiano-Lomoriello, Vincenzo
collection PubMed
description PURPOSE: To test the diagnostic power of Pocket Size Imaging Device (PSID) in detecting early signs of right heart (RH) involvement in regular smokers (RS) free of overt cardiac involvement. METHODS: One-hundred-forty-three regular smokers and 51 healthy controls, comparable for age and sex, underwent physical exam (PE), PSID exam and standard echocardiography. Based on a simplified Boston score, ≥1 of clinical signs (jugular venous distension, hepatomegaly, peripheral pitting oedema and abnormal pulmonary sounds) were considered indicative of RH involvement. A composite score (1 to 4) obtained by summing the points of four quantitative RH abnormalities detectable by PSID (inferior vena cava [IVC] dilatation, reduced IVC respiratory variation, right ventricular dilatation and right atrial dilatation), was generated and ≥1 of PSID abnormal signs was considered indicative of RH involvement. RESULTS: Boston score was not significantly different between the two groups. By using PSID, smokers exhibited greater IVC diameter (p < 0.0001), right atrial diameter (p < 0.002) and higher PSID score (p < 0.005) than controls. Compared to PE, the additional diagnostic power of PSID (≥1 abnormal sign of both Boston and PSID score) was 44.9 % in smokers. By dividing smokers in tertiles according to number of cigarettes per day, the third tertile showed the largest values of both IVC and right atrial dimension. Differences were confirmed by standard echocardiography. Reproducibility of PSID measurements and concordance of linear measurements between PSID and standard echo measurements was very good except for concordance of right ventricular basal diameter. CONCLUSIONS: PSID detects early ultrasound signs of RH involvement in regular otherwise healthy smokers in comparison with PE.
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spelling pubmed-45112322015-07-23 Early markers of right heart involvement in regular smokers by Pocket Size Imaging Device Schiano-Lomoriello, Vincenzo Esposito, Roberta Santoro, Ciro de Simone, Giovanni Galderisi, Maurizio Cardiovasc Ultrasound Research PURPOSE: To test the diagnostic power of Pocket Size Imaging Device (PSID) in detecting early signs of right heart (RH) involvement in regular smokers (RS) free of overt cardiac involvement. METHODS: One-hundred-forty-three regular smokers and 51 healthy controls, comparable for age and sex, underwent physical exam (PE), PSID exam and standard echocardiography. Based on a simplified Boston score, ≥1 of clinical signs (jugular venous distension, hepatomegaly, peripheral pitting oedema and abnormal pulmonary sounds) were considered indicative of RH involvement. A composite score (1 to 4) obtained by summing the points of four quantitative RH abnormalities detectable by PSID (inferior vena cava [IVC] dilatation, reduced IVC respiratory variation, right ventricular dilatation and right atrial dilatation), was generated and ≥1 of PSID abnormal signs was considered indicative of RH involvement. RESULTS: Boston score was not significantly different between the two groups. By using PSID, smokers exhibited greater IVC diameter (p < 0.0001), right atrial diameter (p < 0.002) and higher PSID score (p < 0.005) than controls. Compared to PE, the additional diagnostic power of PSID (≥1 abnormal sign of both Boston and PSID score) was 44.9 % in smokers. By dividing smokers in tertiles according to number of cigarettes per day, the third tertile showed the largest values of both IVC and right atrial dimension. Differences were confirmed by standard echocardiography. Reproducibility of PSID measurements and concordance of linear measurements between PSID and standard echo measurements was very good except for concordance of right ventricular basal diameter. CONCLUSIONS: PSID detects early ultrasound signs of RH involvement in regular otherwise healthy smokers in comparison with PE. BioMed Central 2015-07-23 /pmc/articles/PMC4511232/ /pubmed/26201963 http://dx.doi.org/10.1186/s12947-015-0024-5 Text en © Schiano-Lomoriello et al. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Schiano-Lomoriello, Vincenzo
Esposito, Roberta
Santoro, Ciro
de Simone, Giovanni
Galderisi, Maurizio
Early markers of right heart involvement in regular smokers by Pocket Size Imaging Device
title Early markers of right heart involvement in regular smokers by Pocket Size Imaging Device
title_full Early markers of right heart involvement in regular smokers by Pocket Size Imaging Device
title_fullStr Early markers of right heart involvement in regular smokers by Pocket Size Imaging Device
title_full_unstemmed Early markers of right heart involvement in regular smokers by Pocket Size Imaging Device
title_short Early markers of right heart involvement in regular smokers by Pocket Size Imaging Device
title_sort early markers of right heart involvement in regular smokers by pocket size imaging device
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511232/
https://www.ncbi.nlm.nih.gov/pubmed/26201963
http://dx.doi.org/10.1186/s12947-015-0024-5
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