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Expression of a heat-stable NADPH-dependent alcohol dehydrogenase in Caldicellulosiruptor bescii results in furan aldehyde detoxification

BACKGROUND: Compounds such as furfural and 5-hydroxymethylfurfural (5-HMF) are generated through the dehydration of xylose and glucose, respectively, during dilute-acid pretreatment of lignocellulosic biomass and are also potent microbial growth and fermentation inhibitors. The enzymatic reduction o...

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Detalles Bibliográficos
Autores principales: Chung, Daehwan, Verbeke, Tobin J, Cross, Karissa L, Westpheling, Janet, Elkins, James G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511240/
https://www.ncbi.nlm.nih.gov/pubmed/26203301
http://dx.doi.org/10.1186/s13068-015-0287-y