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The c-MYC-ABCB5 axis plays a pivotal role in 5-fluorouracil resistance in human colon cancer cells

c-MYC overexpression is frequently observed in various cancers including colon cancer and regulates many biological activities such as aberrant cell proliferation, apoptosis, genomic instability, immortalization and drug resistance. However, the mechanism by which c-MYC confers drug resistance remai...

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Detalles Bibliográficos
Autores principales: Kugimiya, Naruji, Nishimoto, Arata, Hosoyama, Tohru, Ueno, Koji, Enoki, Tadahiko, Li, Tao-Sheng, Hamano, Kimikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511355/
https://www.ncbi.nlm.nih.gov/pubmed/25689483
http://dx.doi.org/10.1111/jcmm.12531